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Lampsilis cardium is a species of mussels in the family unionid freshwater mussels. They are listed as near threatened by IUCN. They are associated with freshwater habitat. Individuals can grow to 110 mm.

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EOL has data for 8 attributes, including:

Known occurrences, collected specimens and observations of Lampsilis cardium Rafinesque 1820. View this species on GBIF