Injury, recovery, and death, in relation to conductivity and permeability

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Identifier: injuryrecoveryd00oste (find matches)
Title: Injury, recovery, and death, in relation to conductivity and permeability
Year: 1922 (1920s)
Authors: Osterhout, W. J. V. (Winthrop John Van Leuven), 1871-1964
Subjects: Physiology Electric conductivity Death (Biology)
Publisher: Philadelphia London : J.B. Lippincott Company
Contributing Library: Robarts - University of Toronto
Digitizing Sponsor: University of Toronto

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06 n Fig. 73.—Curves showing antagonism between NaCl and nicotine. Ordinates representnet electrical resistance of Laminaria agardhii (expressed as per cent, of the normal); abscissffirepresent concentrations of nicotine added to 0.52 M NaCl. The resistance of the controlat 18>^ hours was 94%. Average of two experiments; probable error of the mean less than 3% of the mean. point) in 0.52 M NaCl, as well as in 0.52 M NaCl to whichsufficient nicotine has been added to make the concentra-tion 0.01 M. In NaCl 0.52 M plus nicotine 0.002 M theresistance has dropped to 49.5% (i.e., the tissue is about ANTAGONISM 171 half dead). It is evident that nicotine antagonizes theaction of NaCl by inhibiting the fall of resistance whichoccurs in pure NaCl. The upper curve (2 hours) showseven more pronounced antagonism. The results with caffeine (Pig. 74) are similar exceptthat the curve does not fall as rapidly with increasing 8oi%
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.02 .04 .06 n Fig. 74.—Curves showing antagoni.sm between NaCl and caffeine. Ordinates represent netelectrical resistance of Laminaria agardhii (expressed as per cent, of the normal); abscissaerepresent concentrations of caffeine added to 0.52 M NaCl. The resistance of the controlat 18.J^ hours was 96%. Average of two experiments; probable error of the mean less than 5% of the mean. concentrations of alkaloid. With cevadine (Fig. 75) thecurve falls much more rapidly, the maximum being in theneighborhood of 0.005 M cevadine sulfate. Here death 172 INJURY, RECOVERY, AND DEATH is more rapid, the tissue being killed in 18 hours or less,even in the most favorable solution. The experiments with cevadine were carried out dur- 8oi%

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